Police are investigating an aggravated burglary after they were called to a house in Rectory Road in Sible Hedingham shortly before 4.40am yesterday.
Officers arrived to find the householder inside the premises suffering from a gunshot wound to his leg.
A search of the area was carried out but the suspects were not located.
The victim has been taken to hospital for treatment to serious injuries to his leg.
Police have remained at the scene carrying out forensic searches and house to house enquiries.
Investigating officer, Detective Sergeant Mark Cadd, said: “Two men forced entry to the house in the early of hours of the morning and threatened the householder, a man in his 40s.
He locked himself in a bedroom and it is believed a gun was then fired through the door injuring him.
The two men have then fled from the property and at this time it is not believed that anything has been taken.
The two suspects are both white, aged in their 20s, of slim build and wearing dark clothing.
One of them is described as bald.
This was an extremely distressing incident for the victim and he has suffered life-changing injuries which have left him in great pain.
I urgently need to find the men responsible and I would appeal for anyone who saw any suspicious behaviour in Sible Hedingham, either before or after the burglary, to call me at Essex Police on 101.
Alternatively they can ring Crimestoppers on 0800 555 111, it offers rewards of up to £1,000 for information leading to the arrest or conviction of offenders.”